
Course Title: Lab Testing in Assessment of Substance Use Disorders
Presenter(s): Kevin A. Sevarino, MD, PhD
Course Description: Lab testing in the assessment of substance use disorders may involve many different substrates, though urine drug testing (UDT) dominates clinical practice. This course is meant to provide a short guide to effective use of lab testing in the treatment of the patient with a substance use disorder, which, to a surprising degree, is often misused or misunderstood. The course describes the clinical role of lab testing to guide treatment and not to be punitive. To properly use and interpret UDT, it reviews common false positives and false negatives that might occur in the immunologic-based first step in UDT. To understand confirmatory gas chromatography/mass spectrometry, it goes on to describe the metabolism of common opioids and benzodiazepines, because the detected substance is often just a downstream metabolite of several possible parent compounds to which the patient was exposed. The course concludes with a discussion of the difference between UDT for clinical purposes versus forensic ones.
Educational Objectives:
At the conclusion of this activity, participants should be able to:
- Discuss clinical issues in performing urine drug testing (UDT)
- Identify the basic types of UDT and when they should be used
- Interpret laboratory results in the context of opioid and benzodiazepine metabolism
- Appropriately use lab testing in the management of patients with SUD
Curriculum Overview: Healthcare professionals are often on the front lines of treating substance use disorders (SUDs), yet many have limited formal training in this area. The SUD 101 Core Curriculum is designed to build a strong foundation in current research, evidence-based practices, and available resources.
The curriculum includes:
- Foundational Courses: Eight interactive, case-based courses that simulate real-world clinical scenarios and provide foundational SUD training
- Supplemental Courses: These courses offer a deeper exploration of specialized topics and expand on core concepts
Together, these courses enhance healthcare professionals’ competence and confidence in caring for patients with SUDs across the continuum of care, with a particular focus on opioid use disorders (OUD).
This is a foundational course within the SUD 101 Core Curriculum. Visit the SUD 101 Core Curriculum page to explore additional educational trainings as new courses become available.