About: This session will provide an in-depth look at the evolving opioid overdose crisis, focusing on the latest trends and data shaping the epidemic. We'll explore how patterns of use, demographics, and overdose outcomes are shifting, and discuss the underlying factors contributing to these changes. The presentation will also highlight emerging opportunities for prevention, treatment, and harm reduction, with a focus on innovative strategies and policy responses. Attendees will leave the session prepared to move into smaller working groups to discuss actionable insights for addressing its challenges in their communities. Presenter: Alexander Y. Walley, MD, MSc