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Methadone and Buprenorphine-Associated Drug-Drug Interactions

Presenter(s): Andrew Saxon, MD


Target Audience: This activity is designed for physicians, nurses, physician assistants, pharmacists, and the healthcare team. This activity is accredited for physicians, nurses, physician assistants, pharmacists, interprofessional team members, and other health professionals.

Credit Designations Available: AMA PRA Category 1 Credit™, AAPA Category 1 CME, Nursing Contact Hours, Pharmacy CE Credit, Interprofessional Continuing Education (IPCE) Credit

Module Description: This module reviews the following key data points which are important to primary care providers: 1) the current epidemiologic data on drug-drug interactions between opioids and other medications, 2) possible explanations for increases in drug-drug interactions, 3) physiological and pharmacokinetic basis for adverse drug interactions, and 4) strategies for reducing risk for adverse drug interactions.


Educational Objectives:

  • Compare epidemiologic data on drug-drug interactions between opioids and other medications
  • Review possible explanations for drug- drug interactions
  • Describe physiological and pharmacokinetic basis for adverse drug interactions
  • Identify strategies for reducing risk
Certificate Instructions

How to obtain your Certificate:

In order to document your participation in the training, please follow the steps below to obtain your Certificate.

  1. Course Content: Complete the pre-reflection question and view the recorded presentation.

  2. Click Survey and answer the questions to the best of your ability.
    Upon completion of this survey, it will unlock and allow you to proceed to the final course evaluation. 

  3. Click Evaluation to complete the final PCSS course evaluation.

  4. Following your completion of the evaluation, you must select and claim CE or your preferred certificate type on the next page. Once claimed, a download button will appear in your transcript. If you do not see the download button or can not access your certificate, return to the course evaluation, and claim your preferred credit/certificate.

If you have any questions or you do not receive your certificate, please email 

Availability: On-Demand
Expires on Mar 16, 2026
Cost: FREE
Credit Offered:
1 CME Credit
1 PA-CME Credit
1 Other Professionals Credit
1 Nursing Credit
1 Pharmacy Credit
1 IPCE Credit
The content on this site is intended solely to inform and educate medical professionals. This site shall not be used for medical advice and is not a substitute for the advice or treatment of a qualified medical professional.

Funding for this initiative was made possible by cooperative agreement no. 1H79TI086770 and grant no. 1H79TI085588 from SAMHSA. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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