PCSS-MAUD Webinar: The Intersection of Alcohol, Depression, and Suicide-Slides

Slides

Pdf Summary

The webinar "Drowning Sorrows: The Intersection of Alcohol, Depression, and Suicide," presented by Dr. Rebecca A. Payne, addresses the complex relationship between Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD), and suicide risk. AUD and MDD frequently co-occur, with depression being the most common psychiatric disorder among people with AUD, significantly worsening outcomes for both conditions. The session highlights that individuals with both disorders have increased suicide risk, with alcohol use—both chronic and acute intoxication—amplifying suicidal behavior.<br /><br />Epidemiological data reveal high prevalence rates of alcohol use and AUD in the U.S., alongside substantial rates of major depressive episodes. The relationship between AUD and depression is bidirectional and influenced by gender, with women more prone to depression preceding AUD, whereas men more often develop depression following AUD.<br /><br />Diagnostic criteria for MDD, persistent depressive disorder, substance-induced depressive disorder, and AUD were reviewed, underscoring the necessity of thorough clinical evaluation and suicide risk assessment that considers static and dynamic risk factors and protective factors.<br /><br />Treatment approaches combine evidence-based pharmacotherapy and psychosocial interventions. FDA-approved medications for AUD include naltrexone, acamprosate, disulfiram, topiramate, and gabapentin, with naltrexone and acamprosate recommended as first-line treatments. For depression, various classes of antidepressants (SSRIs, SNRIs, atypical agents) and psychotherapies such as cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) are effective. Notably, antidepressants should only be used for AUD patients if they have a co-occurring depressive disorder, as they do not reduce alcohol use by themselves. Combination treatment tailoring pharmacotherapy and psychotherapy is advised for co-occurring disorders.<br /><br />The webinar concluded that integrated, individualized treatment strategies for patients with co-occurring AUD and MDD are safe and effective in improving clinical outcomes and reducing suicide risk. It stressed the importance of appropriately assessing and managing these intertwined conditions within healthcare settings.

Keywords

Alcohol Use Disorder

Major Depressive Disorder

Suicide Risk

Co-occurring Disorders

Epidemiology

Gender Differences

Diagnostic Criteria

Pharmacotherapy

Psychosocial Interventions

Integrated Treatment