Module 1: Xylazine in the Era of Synthetic Street Drugs-Slides

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Pdf Summary

The document discusses the impact of xylazine on people who use drugs, particularly in the context of synthetic street drugs. The SAMHSA-funded Opioid Response Network provides resources and technical assistance to address the opioid crisis and stimulant use at the community level. The use of xylazine as an additive in drugs like fentanyl is increasing and impacting health outcomes, with xylazine becoming prevalent in certain regions like the Rustbelt. Xylazine is highlighted for its role in extending the effects of other drugs, such as fentanyl, which may have deficiencies in providing a sustained high. The document also touches on the emergence of medetomidine as a replacement or complement to xylazine, and the rise of methamphetamine in street drug markets.<br /><br />Issues related to xylazine use include overdose deaths, skin wounds, withdrawal symptoms, and potential replacement with other substances like medetomidine. The text also emphasizes the need for harm reduction strategies in response to the shifting landscape of synthetic drugs, such as providing safe supply and establishing overdose prevention centers. The document urges a comprehensive understanding of the narcotics supply chain to develop efficient public health interventions without stigmatizing drug users or sellers. Tackling the evolving challenges posed by synthetic drugs like xylazine requires a multi-faceted approach that prioritizes community engagement and evidence-based strategies to address the complex health outcomes associated with these substances.

Keywords

xylazine

synthetic street drugs

SAMHSA-funded Opioid Response Network

opioid crisis

stimulant use

fentanyl

Rustbelt

medetomidine

methamphetamine

harm reduction strategies