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Managing Opioid Use Disorder Care in the Era of Fe ...
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Video Summary
Dr. John Mariani discusses managing opioid use disorder in the era of fentanyl. He emphasizes the need for evidence-based practices in the prevention and treatment of opioid use disorders, particularly in prescribing medications. While there is a lack of scientific evidence specifically focused on fentanyl users, Dr. Mariani shares his clinical observations and experiences. He notes that fentanyl has led to a rise in overdose fatalities and a loss of confidence in traditional treatment methods. Fentanyl's high potency and lipophilic nature make it more challenging to treat compared to other opioids like heroin or oxycodone. Dr. Mariani explains the pharmacokinetic and pharmacodynamic differences between fentanyl and other opioids and how these differences may impact treatment outcomes. He also discusses some strategies for managing fentanyl use disorder, such as low-dose and high-dose buprenorphine inductions, as well as the use of extended-release injectable buprenorphine and naltrexone. While there is limited evidence and more research is needed to fully understand the most effective approaches, Dr. Mariani emphasizes the importance of tailoring treatment to individual patients' needs and adjusting strategies based on clinical circumstances. He concludes by highlighting the need for more studies and evidence-based guidelines to guide clinicians in managing fentanyl use disorder.
Keywords
Substance Use Screening
Primary Care
Screening Tools
Implementation Guidance
Dr. Jennifer McNeely
Prevalence of Substance Use
TAPS Tool
Electronic Health Records
Referral and Treatment Options
opioid use disorder
fentanyl
evidence-based practices
treatment
overdose fatalities
pharmacokinetic
pharmacodynamic
buprenorphine inductions
naltrexone
tailoring treatment
The content on this site is intended solely to inform and educate medical professionals. This site shall not be used for medical advice and is not a substitute for the advice or treatment of a qualified medical professional.
Funding for this initiative was made possible by cooperative agreement no. 1H79TI086770 and grant no. 1H79TI085588 from SAMHSA. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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