7789 Opioid Use Disorder 101-Slides

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The Opioid Response Network (ORN), funded by the Substance Abuse and Mental Health Services Administration (SAMHSA), provides resources and technical assistance to communities to address the opioid and stimulant crisis. The ORN offers evidence-based prevention, treatment, recovery, and harm reduction techniques, facilitated by local, experienced consultants.<br /><br />Addiction is a chronic disease affecting brain reward, motivation, memory, and related circuitry, leading to compulsive substance use despite harmful consequences. Opioids, which are drugs that act on the brain's opioid receptors, can reduce pain and induce euphoria, making them highly addictive. Misuse can lead to physical changes in the brain, tolerance, dependency, and severe withdrawal symptoms, as well as potential overdose and death.<br /><br />Commonly misused prescription opioids include Codeine, Oxycodone, Hydrocodone, Meperidine, Hydromorphone, Fentanyl, and Morphine. Tolerance to opioids necessitates higher doses to achieve the same effect, and dependency primarily serves to avoid withdrawal rather than to achieve euphoria.<br /><br />In terms of treatment, Medications for Opioid Use Disorder (MOUD) such as Methadone and Buprenorphine are used. Methadone is a full opioid receptor activator, often used for individuals with high opioid use histories, while Buprenorphine is a partial receptor activator, sometimes combined with Naloxone to prevent misuse. Both medications help reduce cravings and withdrawal symptoms, supporting long-term recovery.<br /><br />There are notable disparities in access to opioid treatment, leading to increased overdose deaths, particularly among Black populations since 2013. Overdose rates have been tracked in states like Oregon, highlighting the ongoing crisis and underscoring the need for equitable treatment access.<br /><br />The document emphasizes the importance of community involvement in tackling the opioid crisis and solicits feedback to improve the experience and effectiveness of ORN initiatives.
Keywords
Opioid Response Network
SAMHSA
opioid crisis
stimulant crisis
addiction
treatment
MOUD
Methadone
Buprenorphine
overdose